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Mushtaq Bilal, PhDResearcher @ Syddansk Universitet
Mushtaq Bilal, PhDResearcher @ Syddansk UniversitetLoved by 1 million+ researchers from
Popular papers to read
Exploring the Limits of Transfer Learning with a Unified Text-to-Text Transformer
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Top papers of 2023
Data from Expression of Aurora A (but Not Aurora B) Is Predictive of Survival in Breast Cancer
31 Mar 2023
In this paper , the authors used cytokeratin to define pixels as breast cancer (tumor mask) within the array spot and measured Aurora A and B expression within the mask using Cy5-conjugated antibodies.Data from Enhanced Antitumor Efficacy of Low-Dose Etoposide with Oncolytic Herpes Simplex Virus in Human Glioblastoma Stem Cell Xenografts
31 Mar 2023
In this article , the authors investigated a combinatorial approach of low-dose etoposide with an oncolytic HSV to enhance antitumor activity and limit drug toxicity.Data from Combination Therapy of Bortezomib with Novel Targeted Agents: An Emerging Treatment Strategy
31 Mar 2023
A number of clinical trials evaluating combinations of targeted agents with bortezomib, the first-in-class proteasome inhibitor, have been initiated, with the objective of enhancing its single agent activity in hematologic malignancies (myeloma, mantle cell lymphoma), as well as expanding its efficacy in solid tumors as mentioned in this paper .Data from <i>Jumonji Domain Containing 1A</i> Is a Novel Prognostic Marker for Colorectal Cancer: <i>In vivo</i> Identification from Hypoxic Tumor Cells
31 Mar 2023
In this article , the authors identify hypoxia-inducible and prognostic markers from colorectal cancer (CRC) liver metastases using laser capture microdissection, in parallel with five CRC cell lines cultured under hypoxic conditions.Data from Association between Upper Digestive Tract Microbiota and Cancer-Predisposing States in the Esophagus and Stomach
31 Mar 2023
Wang et al. as mentioned in this paper examined the relationship between upper digestive tract microbiota and two cancer-predisposing states, serum pepsinogen I/pepsinogen II ratio (PGI/II) and esophageal squamous dysplasia (ESD) in a cross-sectional design.Data from Tumor-Infiltrating Macrophages Are Associated with Metastasis Suppression in High-Grade Osteosarcoma: A Rationale for Treatment with Macrophage Activating Agents
31 Mar 2023
In this article , the authors investigated the development of metastasis by studying tumor cells and their stromal context, and found that TAMs are associated with reduced metastasis and improved survival in high grade osteosarcoma.Data from Enhancement of T-cell–Mediated Antitumor Response: Angiostatic Adjuvant to Immunotherapy against Cancer
31 Mar 2023
In this paper , the authors investigated the temporal dynamics of cellular and molecular events that occur in the tumor microenvironment during tumor progression and angiostatic intervention, and showed that a combination of angiogenesis inhibitors and T-cell transfer significantly improves tumor growth inhibition.Data from Oncolytic Herpes Simplex Virus Vector G47Δ in Combination with Androgen Ablation for the Treatment of Human Prostate Adenocarcinoma
31 Mar 2023
In this article , a herpes simplex virus type 1 vector G47Δ was constructed by deleting the α47 gene and the promoter region of the US11 gene from G207.Data from Pharmacokinetic Analysis and Phase 1 Study of MRX-1024 in Patients Treated with Radiation Therapy with or without Cisplatinum for Head and Neck Cancer
31 Mar 2023
In this paper , the authors evaluated the safety and utility of D-methionine (D-met) using a phase 1 clinical trial with 25 patients who were administered with D-met concurrent with radiation therapy and weekly cisplatinum.Data from High-Dose Antiangiogenic Therapy for Glioblastoma: Less May Be More?
31 Mar 2023
In this article , angiogenesis targeting in glioblastoma rapidly reduces vascular permeability and contrast enhancement on MRI and prolongs progression-free survival, however, the long-term efficacy of bevacizumab and other antiangiogenic agents is limited, because of the rapid development of resistance.Data from Association of an Extracellular Matrix Gene Cluster with Breast Cancer Prognosis and Endocrine Therapy Response
31 Mar 2023
In this article , an extracellular matrix (ECM) gene cluster associated with resistance to first-line tamoxifen therapy of patients with metastatic breast cancer was found.Data from T-Cell Coregulatory Molecule Expression in Urothelial Cell Carcinoma: Clinicopathologic Correlations and Association with Survival
31 Mar 2023
In this article , the authors evaluated expression of the T-cell coregulators B7H1, B7-H3, and PD-1 in urothelial cell carcinoma (UCC) of the bladder.Data from Safety and Efficacy of Axicabtagene Ciloleucel versus Standard of Care in Patients 65 Years of Age or Older with Relapsed/Refractory Large B-Cell Lymphoma
31 Mar 2023
In this article , axicabtagene ciloleucel (axi-cel) was compared with standard of care (SOC) for patients with relapsed/refractory large B-cell lymphoma.Data from Cleaved Forms of the Urokinase Plasminogen Activator Receptor in Plasma Have Diagnostic Potential and Predict Postoperative Survival in Patients with Ovarian Cancer
31 Mar 2023
In this paper , the authors evaluated the plasma level of different forms of soluble urokinase plasminogen activator receptor (suPAR) as discriminators between malignant, borderline, and benign ovarian tumors and as prognostic markers in patients with ovarian cancer.Data from Second-Generation Anti–Carcinoembryonic Antigen Designer T Cells Resist Activation-Induced Cell Death, Proliferate on Tumor Contact, Secrete Cytokines, and Exhibit Superior Antitumor Activity <i>In vivo</i>: A Preclinical Evaluation
31 Mar 2023
The second-generation CIR (termed "Tandem" for two signals) was designed to transmit TCR Signal 1 and CD28 Signal 2 to render T cells resistant to AICD and provide prolonged antitumor effect as discussed by the authors .Data from Secretory Leukocyte Protease Inhibitor Antagonizes Paclitaxel in Ovarian Cancer Cells
31 Mar 2023
In this paper , the secretory leukocyte protease inhibitor (SLPI) is shown to be a survival factor for ovarian cancer and the authors hypothesize that SLPI may antagonize paclitaxel injury.Data from Prognostic Value of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (TRAIL) and TRAIL Receptors in Renal Cell Cancer
31 Mar 2023
In this article , the effect of TRAIL and TRAIL-R2 expression levels on the prognosis of patients with renal cell carcinomas (RCC) was investigated and the authors found that high TRAIL expression was associated with a shorter disease-specific survival.Data from Expression of Sorafenib Targets in Melanoma Patients Treated with Carboplatin, Paclitaxel and Sorafenib
31 Mar 2023
In this paper , the expression of VEGF-R2 was associated with response to paclitaxel (SCP), whereas high ERK1/2 is associated with resistance, indicating that ERK 1/2-expressing tumors are biologically more aggressive.Data from Down-regulation of ZIP4 by RNA Interference Inhibits Pancreatic Cancer Growth and Increases the Survival of Nude Mice with Pancreatic Cancer Xenografts
31 Mar 2023
In this paper , the role of the zinc transporter, ZIP4, in pancreatic cancer progression was investigated using short hairpin RNA using retrovirus vectors, and the stable cells were characterized using a nude mouse xenograft model.Data from JNJ-26481585, a Novel Second-Generation Oral Histone Deacetylase Inhibitor, Shows Broad-Spectrum Preclinical Antitumoral Activity
31 Mar 2023
JNJ-26481585 as mentioned in this paper is a second-generation class I histone deacetylase (HDAC) inhibitor with prolonged pharmacodynamic response, which results in superior antitumoral efficacy.Data from Systemic Administration of a Conditionally Replicating Adenovirus, Targeted to Angiogenesis, Reduced Lung Metastases Burden in Cotton Rats
31 Mar 2023
In this paper , an adenovirus that is transcriptionally targeted to replicate in angiogenic endothelial cells, was constructed, by replacing the E1 promoter with the modified pre-endothelin-1 promoter, PPE-1-3x, previously shown to induce specific transcription in angiovisual endothelial cell.Data from Antiangiogenic and Antitumor Activity of 6-(2-Aminoethyl)Amino-5-Chlorouracil, a Novel Small-Molecule Inhibitor of Thymidine Phosphorylase, in Combination with the Vascular Endothelial Growth Factor-Trap
31 Mar 2023
A small-molecule inhibitor of the catalytic activity of platelet-derived endothelial cell growth factor, 6-(2-aminoethyl)amino-5-chlorouracil (AEAC), was tested for antiangiogenic and antitumor activity in human cancer xenografts as discussed by the authors .Data from Genetic and Expression Analysis of HER-2 and EGFR Genes in Salivary Duct Carcinoma: Empirical and Therapeutic Significance
31 Mar 2023
In this article , Salivary duct carcinoma overexpresses epidermal growth factor receptor (EGFR) and HER-2, although the underlying mechanisms remain undefined.Data from Herbal Extract of <i>Wedelia chinensis</i> Attenuates Androgen Receptor Activity and Orthotopic Growth of Prostate Cancer in Nude Mice
31 Mar 2023
W. chinensis extract (4 or 40 mg/kg/d for 24-28 days) attenuated the growth of prostate tumors in nude mice implanted at both subcutaneous (31% and 44%, respectively) and orthotopic (49% and 49% respectively) sites as mentioned in this paper .Data from Combined Functional Genome Survey of Therapeutic Targets for Hepatocellular Carcinoma
31 Mar 2023
In this article , siRNA-based secondary screening of genes required for hepatocellular carcinoma (HCC) cell proliferation was used to identify candidate therapeutic targets for HCC.Data from SC68896, a Novel Small Molecule Proteasome Inhibitor, Exerts Antiglioma Activity <i>In vitro</i> and <i>In vivo</i>
31 Mar 2023
In this article , the authors characterized the antitumor properties of SC68896, a novel small molecule proteasome inhibitor, for the treatment of malignant glioma.Data from Genomic and Expression Profiling of Glioblastoma Stem Cell–Like Spheroid Cultures Identifies Novel Tumor-Relevant Genes Associated with Survival
31 Mar 2023
In this paper , a comparative genomic hybridization of spheroid cultures derived from 20 glioblastomas was carried out to determine genes with differential expression compared with normal brain tissue and to nonneoplastic brain spheroids.Data from Ras/Raf-1/MAPK Pathway Mediates Response to Tamoxifen but not Chemotherapy in Breast Cancer Patients
31 Mar 2023
In this article , the authors investigated whether the expression and activation of the key components of the Ras pathway influenced clinical outcome, to test the hypothesis that activation of Ras/Raf-1/mitogen-activated protein kinase (MAPK) pathway plays an important role in the development and progression of cancer, and may influence response to treatments such as tamoxifen and chemotherapy.Data from Tumor Microenvironment of Metastasis in Human Breast Carcinoma: A Potential Prognostic Marker Linked to Hematogenous Dissemination
31 Mar 2023
In this article , the authors defined TMEM as the tripartite arrangement of an invasive carcinoma cell, a macrophage, and an endothelial cell, and determined if TMEM density in human breast carcinoma samples predicts the development of systemic, hematogenous metastases.Data from Germline Variation in Apoptosis Pathway Genes and Risk of Non–Hodgkin's Lymphoma
31 Mar 2023
In this paper , the authors conducted a comprehensive evaluation of 36 apoptosis pathway genes with risk of non-Hodgkin's lymphoma (NHL) and found that three of them were associated with NHL risk.Data from Anti–Programmed Death-1 Synergizes with Granulocyte Macrophage Colony-Stimulating Factor–Secreting Tumor Cell Immunotherapy Providing Therapeutic Benefit to Mice with Established Tumors
31 Mar 2023
In this article , the authors evaluated granulocyte macrophage colony-stimulating factor (GM-CSF)secreting tumor cell immunotherapy, which is known to stimulate potent and longlasting antigen-specific immune responses, in combination with PD-1 blockade, which has been shown to augment cellular immune responses.Data from Clinical Benefit of Allogeneic Melanoma Cell Lysate–Pulsed Autologous Dendritic Cell Vaccine in MAGE-Positive Colorectal Cancer Patients
31 Mar 2023
In this article , the clinical benefit of an allogeneic melanoma cell lysate (MCL)-pulsed autologous dendritic cell (DC) vaccine in advanced colorectal cancer patients expressing at least one of six MAGE-A antigens overexpressed by the cell line source was evaluated.Data from Involvement of a Novel Chemokine Decoy Receptor CCX-CKR in Breast Cancer Growth, Metastasis and Patient Survival
31 Mar 2023
In this paper , the role of CCX-CKR in human breast cancer was investigated in cell lines, animal models, and clinical samples, and it was shown that CCXCKR is a negative regulator of growth and metastasis in breast cancer mainly by sequestration of homeostatic chemokines and subsequent inhibition of intratumoral neovascularity.Data from Inflammatory-Related Genetic Variants in Non–Muscle-Invasive Bladder Cancer Prognosis: A Multimarker Bayesian Assessment
31 Mar 2023
In this article , the association of SNPs in inflammatory-related genes with non-muscle-invasive bladder cancer (NMIBC) risk of recurrence and risk-of-progression was evaluated using Cox regression single-marker (SMM) and multimarker methods (MMM) Bayes A and Bayesian LASSO.Data from A Pooled Analysis of Smoking and Colorectal Cancer: Timing of Exposure and Interactions with Environmental Factors
31 Mar 2023
In this article , the authors conducted a pooled analysis of eight studies, including 6,796 colorectal cancer cases and 7,770 controls, to evaluate the association between cigarette smoking history and CRC risk and investigate potential effect modification by other risk factors.Data from The Effect of Ketoconazole on the Pharmacokinetics and Pharmacodynamics of Ixabepilone: A First in Class Epothilone B Analogue in Late-Phase Clinical Development
31 Mar 2023
In this paper , a clinical drug interaction study in humans using ketoconazole as an inhibitor of CYP3A4 was conducted to determine if ixabepilone is a substrate for cytochrome P450 3A4 and if its metabolism by this enzyme is clinically important.Data from Evaluation of Colon Cancer–Specific Antigen 2 as a Potential Serum Marker for Colorectal Cancer
31 Mar 2023
In this article , the authors used an indirect ELISA on serum samples obtained from two institutions, and evaluated CCSA-2 as a serum-based colon cancer marker with high sensitivity and specificity.Data from Heterogeneous Nuclear Ribonucleoprotein G Shows Tumor Suppressive Effect against Oral Squamous Cell Carcinoma Cells
31 Mar 2023
In this article , the expression levels of hnRNP G protein in normal, precancerous, and malignant oral tissues by immunohistochemistry were investigated and it was shown that hn RNP G is a tumor suppressor against HOSCC.Data from Nuclear Localization of Signal Transducer and Activator of Transcription 3 in Head and Neck Squamous Cell Carcinoma Is Associated with a Better Prognosis
31 Mar 2023
In this paper , the expression pattern of STAT3 was correlated with outcome in two independent data sets and associations were validated in a second independent cohort of 58 patients with confirmed HNSCC enrolled in the Early Detection Research Network-sponsored study.Data from Diminished Sensitivity of Chronic Lymphocytic Leukemia Cells to ABT-737 and ABT-263 Due to Albumin Binding in Blood
31 Mar 2023
In this article , the authors compared ABT-737 and AbT-263 in terms of their ability to induce apoptosis in clinically relevant cellular models of chronic lymphocytic leukemia (CLL).Data from Targeting Autophagy Augments <i>In Vitro</i> and <i>In Vivo</i> Antimyeloma Activity of DNA-Damaging Chemotherapy
31 Mar 2023
In this article , the effects of DNA damage on autophagy in multiple myeloma (MM) cells and elucidate its underlying molecular mechanism were investigated and the impacts of pharmacologic or genetic inhibition on DNA damage-induced apoptosis were examined.Data from Phase I Dose Finding Studies of Obatoclax (GX15-070), a Small Molecule Pan-BCL-2 Family Antagonist, in Patients with Advanced Solid Tumors or Lymphoma
31 Mar 2023
In this article , the authors evaluated the safety and tolerability of weekly 1-hour and 3-hour infusions of obatoclax, respectively, for BCL-2 antiapoptotic proteins.Data from Gene Expression Profiling of Papillary Thyroid Carcinoma Identifies Transcripts Correlated with <i>BRAF</i> Mutational Status and Lymph Node Metastasis
31 Mar 2023
In this article , gene expression profiles of three Serial Analysis of Gene Expression libraries generated from thyroid tumors and a normal thyroid tissue were compared to identify genes that might be regulated by abnormal BRAF/MEK/extracellular signal-regulated kinase signaling.Data from Loss of Tuberous Sclerosis Complex-2 Function and Activation of Mammalian Target of Rapamycin Signaling in Endometrial Carcinoma
31 Mar 2023
In this article , the authors determined the frequency of mTOR activation in endometrial carcinoma (primary tumors and cell lines) and investigated PTEN, LKB1, and TSC2 defects as underlying cause(s) of activation.Data from Genetic Changes of Wnt Pathway Genes Are Common Events in Metaplastic Carcinomas of the Breast
31 Mar 2023
In this article , the authors comprehensively determined the prevalence of and mechanism underlying β-catenin and Wnt pathway deregulation using immunohistochemistry for β-Catenin expression and localization and mutational analysis for 36 primary metaplastic carcinomas.Data from The Association between Leisure Time Physical Activity and Pancreatic Cancer Risk in Adults: A Systematic Review and Meta-analysis
31 Mar 2023
A meta-analysis of the association between leisure time physical activity (LTPA) and risk of pancreatic cancer was conducted by as mentioned in this paper to examine subgroups of interest and potential sources of heterogeneity.Data from High-Resolution Array Comparative Genomic Hybridization in Sporadic and Celiac Disease–Related Small Bowel Adenocarcinomas
31 Mar 2023
In this article , the most frequent DNA copy number changes found were gains on 5p15.33-5p12, 7p22.3-7q11.33, and losses on 4p13-4q35.33.Data from Proapoptotic Function of Integrin β<sub>3</sub> in Human Hepatocellular Carcinoma Cells
31 Mar 2023
In this paper , the proapoptotic function of integrin β and its ligands in human hepatocellular carcinoma (HCC) was evaluated by quantitative real-time PCR and Western blot.Top papers of 2022
Immunotherapy for head and neck cancer: present and future.
01 Apr 2022 - Critical Reviews in Oncology Hematology
In this article , the authors report current evidence on immunotherapy in head and neck cancer with updates from the main oncology events as ASCO, AACR and ESMO meetings, focusing on clinical trials results of single agent and combination immunotherapy.Effect of heat treatment on the strength and fracture resistance of a laser powder bed fusion-processed 18Ni-300 maraging steel
01 Apr 2022 - Materials Science and Engineering A-structural Materials Properties Microstructure and Processing
In this paper , the authors investigated how three heat-treatments (direct aging, solution treatment + aging, and thermal cycling + aging) impact microstructure evolution and corresponding mechanical performance of LPBF-processed 18Ni-300 maraging steel.Neuroprotective effects of DHA-derived peroxidation product 4(RS)-4-F4t-neuroprostane on microglia.
01 Apr 2022 - Free Radical Biology and Medicine
In this paper , a non-enzymatic oxidized product of DHA, 4(RS)-4-F4t-Neuroprostane (44FNP), was found to attenuate LPS-induced production of reactive oxygen species (ROS) in both primary and immortalized microglia (BV2).Matrix stiffness enhances cancer-macrophage interactions and M2-like macrophage accumulation in the breast tumor microenvironment.
01 Apr 2022 - Acta Biomaterialia
In this article , the effects of matrix stiffening on intratumor heterogeneity have not been thoroughly studied and the authors applied single-cell RNA sequencing to investigate the differences in the transcriptional landscapes between stiff and compliant MMTV-PyMT mouse mammary tumors.Effect of far infrared and far infrared combined with hot air drying on the drying kinetics, bioactives, aromas, physicochemical qualities of Anoectochilus roxburghii (Wall.) Lindl.
01 Apr 2022 - Lebensmittel-Wissenschaft & Technologie
In this paper , far infrared drying (FID) and far infrared combined with hot air drying (FIHAD) were employed to preserve the quality of Anoectochilus.A semi-analytical one-dimensional model for offshore pile foundations considering effects of pile diameter and aspect ratio
01 Apr 2022 - Ocean Engineering
A semi-analytical 1D model with the eight types of soil reactions is derived from the fishbone frame model for pile foundations of wind turbines, in which the coupling between axial and lateral resistances that matters for large pile diameters and small pile aspect ratios is modeled as the rotational soil reactions as discussed by the authors .Drainage of senescent astrocytes from brain via meningeal lymphatic routes
01 Apr 2022 - Brain Behavior and Immunity
In this article , perivascular spaces and meningeal lymphatic vessels formed a functional route for clearance of senescent astrocytes from the aging brain and mitigated neuroinflammation.Simple Slot Antenna With Polarization Diversity
01 Apr 2022 - IEEE Antennas and Wireless Propagation Letters
In this paper , a dual-feed circularly polarized slot antenna with polarization diversity is proposed, which consists of a circular slot that acts as a radiator, a dual microstrip line as a feeding structure, a slit applied to a ground plane (GND), and a protruded stub.In2O3 Hollow Porous Nanospheres Loaded with Ag Nanoparticles to Achieve Wide Concentration Range Triethylamine Detection
01 Apr 2022 - Materials Research Bulletin
In this article , In2O3 hollow porous nanospheres (HPNSs) loaded with Ag nanoparticles were used for real-time monitoring of Triethylamine (TEA) gas.Frost thickness estimation in a domestic refrigerator using acoustic signals and artificial intelligence
01 Apr 2022 - Expert systems with applications
In this article , an intelligent model and a combination of an active speaker and a simple microphone were used to estimate the amount of accumulated frost on the surface of the evaporator inside a domestic refrigerator.Acoustic residual softening and microstructure evolution of T2 copper foil in ultrasonic vibration assisted micro-tension
01 Apr 2022 - Materials Science and Engineering A-structural Materials Properties Microstructure and Processing
In this article , the softening effect induced by ultrasonic vibration is widely studied due to its advantages in high product quality and processing efficiency, while only a few investigations focus on the residual effect of ultrasonic vibrations, especially for its micro-mechanism.Fate of Escherichia coli artificially inoculated in Tenebrio molitor L. larvae rearing chain for human consumption.
01 Apr 2022 - Food Research International
In this paper , the dynamics of Escherichia coli during the whole living period of Tenebrio molitor larvae (from eggs to pupae) were studied, and the results highlighted a very limited persistence of the pathogen in all analyzed samples.Numerical analysis of noise and gain equalization characteristics of few-mode PbS quantum dots-doped silica fibre amplifier
01 Apr 2022 - Optics Communications
In this paper , a few-mode PbS quantum dot-doped fiber amplifier (FM-PQDFA) was developed and numerically studied, which can effectively amplify the linear polarisation (LP) signal modes, including LP01, LP11, and LP21, in the range 1100-1350 nm.Fault diagnosis of a semi-batch crystallization process through deep learning method
01 Apr 2022 - Computers & Chemical Engineering
In this paper , a coupled method combining convolutional neural network (CNN) with dynamic time warping (DTW) is proposed for fault detection and diagnosis in semi-batch crystallization process based on temperature and flow supersaturation control.Functional and structural properties of cardiotoxin isomers produced by blocking negatively charged groups.
01 Apr 2022 - Archives of Biochemistry and Biophysics
In this paper , the functional roles of Asp40, Asp57, and C-terminal Asn60 in Naja atra cardiotoxin 3 (CTX3) structure and function were investigated by modifying these three carboxyl groups with semicarbazide.Interregional practice variations in the use of local therapy for synchronous colorectal liver metastases in the Netherlands.
01 Apr 2022 - Hpb
In this paper , the authors evaluated the Dutch regional practice variation in treatment of synchronous colorectal liver metastases (CRLM) over time and assess their impact on patients survival.Placenta percreta as a cause of uterine rupture in the second trimester: Case report
01 Apr 2022 - International Journal of Surgery Case Reports
A case of a 33-year-old patient who was admitted to the emergency room for signs of shock at 29 weeks of a poorly supervised pregnancy, secondary to a spontaneous uterine rupture on a previously scarred uterus by a caesarean delivery two years prior to the events was presented in this paper .Irinotecan-loaded ROS-responsive liposomes containing thioether phosphatidylcholine for improving anticancer activity
01 Apr 2022 - Journal of Drug Delivery Science and Technology
In this article , irinotecan (IR)-loaded reactive oxygen species (ROS)-responsive liposomes were developed for improving anticancer activity, which might be an alternative of convenient IR-liposomes.Estimating excess length of stay due to healthcare-associated infections by applying and comparing three time-varying approaches: multistate model, survival regression and matched case control methods.
01 Apr 2022 - Journal of Hospital Infection
In this paper , the authors performed a retrospective analysis of data from a one-year prospective incidence study of healthcare-associated infections (HAIs), in one teaching hospital and one general hospital in NHS Scotland, and compared three time-varying methods: multistate model, multivariable adjusted survival regression, and matched case-control approach.Machine Learning-Based Retention Time Prediction of Trimethylsilyl Derivatives of Metabolites
01 Apr 2022 - Advances in Cardiovascular Diseases
This study challenged predicted retention time when using chemical ionization and electron impact ionization sources in simulated and real cases, demonstrating a good correct identity ranking capability by machine learning, despite observing a limited false identity filtering power in cases where a spectrum or a monoisotopic mass match to multiple candidates.Beauty and popularity in friendship networks—Evidence from migrant schools in China
01 Apr 2022 - Economics Letters
Zhang et al. as mentioned in this paper examined whether physical appearance helps children gain popularity in their friendship networks using data from China's migrant schools using negative binomial models, using appearance scores (created by a facial-recognition program incorporating numerous individuals' appearance preferences) to predict children's network centrality.Implicit Subgrid-Scale Modeling of a Mach 2.5 Spatially Developing Turbulent Boundary Layer
01 Apr 2022 - Entropy
In this article , the authors employ numerically implicit subgrid-scale modeling provided by the well-known streamlined upwind/Petrov-Galerkin stabilization for the finite element discretization of advection-diffusion problems in a Large Eddy Simulation (LES) approach.Vortex signal model based Kalman filter of vortex signal processing method.
01 Apr 2022 - Review of Scientific Instruments
The proposed vortex signal model based Kalman filter of the vortex signal processing method has the advantages of adaptive filtering, better anti-interference ability, and faster filtering speed.Attempts to Stimulate Immunology Responses by Intramuscular and Intraperitoneal Delivery of EPS-Adjuvanted Mannheimiosis Vaccine
01 Apr 2022 - American Journal of Animal and Veterinary Sciences
In this article , a study was conducted on 48 male Sprague Dawley rats to determine the immunological responses of experimental adjuvanted vaccines of Mannheimia haemolytica A2 (MHA) injection and to observe their protection level upon live MHA A2 challenge.Analysis of the release of water-soluble substances from the barren part of the sea buckthorn
01 Apr 2022 - IOP Conference Series: Earth and Environmental Science
In this article , experimental studies of water extraction of the barren part of sea buckthorn, namely bark, wood, leaves and shoots, have been carried out, and the yield of water-soluble substances relative to the feedstock, depending on the temperature and duration of the process.Parents' knowledge, attitude and practices toward oral health of their children with primary dentition: A cross sectional study
01 Apr 2022 - Journal of Medicine in Scientific Research
The poor practice of parents revealed in the present study had a strong negative influence on their children's caries prevalence.Mitochondrial Calcium Overload Promotes Cell Hypertrophy And Energetic Dysfunction In Human Heart Failure.
01 Apr 2022 - Journal of Cardiac Failure
In this paper , the authors measured the expression of MCU on failing human left ventricular tissue obtained at the time of orthotopic heart transplantation or left-ventricular assist device (LVAD) insertion against nonfailing heart tissue samples and after LVAD removal (post-LVAD).Research on prediction algorithm of ship equipment heath condition
01 Apr 2022 - Ocean Engineering
In this paper , an improved dynamic time warping (DTW) algorithm is used to calculate the similarity of two time series, which is then used to extract the relationship between devices, and a multivariate time series forecasting with graph neural networks (MTGNN) structure is established to establish predictive model.TRACES: A Lightweight Browser for Liquid Chromatography–Multiple Reaction Monitoring–Mass Spectrometry Chromatograms
01 Apr 2022 - Metabolites
The development of new software, TRACES, a lightweight chromatogram browser for MRM-based targeted LC-MRM-MS analysis that successfully removed isotopic signals within the MRM chromatograms, helping users avoid inappropriate regions for integration.Laser powder bed fusion of a Nb-based refractory alloy: Microstructure and tensile properties
01 Apr 2022 - Materials Science and Engineering A-structural Materials Properties Microstructure and Processing
In this paper , a laser powder bed fusion (LPBF) was used to fabricate Nb521 (Nb-5W-2Mo-1Zr) parts using quasi-spherical hydride-dehydride (HDH) powders modified by jet milling.MR Imaging of the Knee Posterolateral and Posteromedial Corner Injuries.
01 Apr 2022 - Magnetic Resonance Imaging Clinics of North America
The posteromedial and posterolateral corners of the knee are important areas to consider when assessing the patient with a possible knee injury as mentioned in this paper , and an understanding of the anatomy, associated biomechanics, and typical injury patterns in these regions will improve the value that the radiologist interpreting the MRIs brings to this patient population.Stapler stuck to the lung tissue during thoracoscopic lobectomy: a case report
01 Apr 2022 - Shanghai chest
The strategy may be useful for surgeons to deal an unpredicted similar situation that may occur either for stapler malfunction or for improper use during thoracoscopic left lower lobectomy.Loss of HPV 16- E2 Predicts Disease Free Survival and Promotes Platinum Resistance in Human Papillomavirus-Positive Head and Neck Squamous Cell Carcinoma
01 Apr 2022 - International Journal of Radiation Oncology Biology Physics
In this article , the role of E2 status as a predictive marker in a cohort of oropharyngeal squamous cell carcinoma (OPSCC) patients was evaluated and the role was investigated in treatment response in HPV + head and neck cancer cell line models.An Appraisal of the Legal Regime of Internet Policing in Nigeria
01 Apr 2022 - Journal of Law, Policy and Globalization
In this article , the authors examined internet policing with particular reference to Nigeria and further unraveled some of the challenges face via internet policing in Nigeria, and concluded by making recommendation on how Nigeria will utilize Internet policing in tackling crime.IDF21-0173 Relationship between periodontal disease and gestational diabetes mellitus: A systematic review
01 Apr 2022 - Diabetes Research and Clinical Practice
In this paper , a systematic review is presented to analyze the studies evaluating an association between periodontal disease and GDM, which includes 12 original studies (2 cross-sectional, 4 case control, and 6 cohort or follow-up) and 4 systematic reviews or meta-analyses (MA).The role of narrative structure in the acquisition of european portuguese perfective and imperfective morphology by l1 mandarin chinese learners
01 Apr 2022 - Caderno de Letras
The authors examined the relationship between the use of perfective/imperfective morphology and the narrative grounding and found that the foreground was mostly marked by the perfective morphology, whereas the imperfective tended to be used to mark the background, irrespective of the learners' proficiency levels.Risk factors for QT prolongation with atypical antipsychotics
01 Apr 2022 - The Brown University Psychopharmacology Update
Drug‐induced prolongation of the QT interval can increase risk of developing the life‐threatening, albeit rare, atypical ventricular tachycardia known as torsade de pointes.Difference of co-extracted electron current and beam acceleration in a negative ion source with hydrogen-isotope ions
01 Apr 2022 - Journal of Physics: Conference Series
In this paper , a hydrogen/deuterium negative ion source for a nuclear fusion device is reported, where the suppression of the co-extracted electron current, Ie, is an important issue to ensure the stable beam acceleration.Predictive value of platelet markers in the patients with acute pulmonary thromboembolism
01 Apr 2022 - Studies in Medical Sciences
Evaluation of the relationship between platelet indices and pulmonary thromboembolism severity score using Pearson correlation coefficient (Spearman) test showed that MPV was inversely related to emblism severity, although this difference was not statistically significant.A prospective cohort study of adverse fetomaternal outcomes among overweight, obese, and normal weight pregnant women with term singleton pregnancy in a tertiary care hospital
01 Apr 2022 - Asian journal of medical sciences
Pre-pregnancy intervention for optimization of maternal weight with proper surveillance of every pregnant mother of this subset and vigilant neonatal care may improve the obstetric and perinatal outcome.Technical and economic efficiency of geological and technical measures in gas condensate wells
01 Apr 2022 - Естественные и технические науки
In this paper , the authors presented the predictive management of technical measures of the well of gas well and showed the results of the technical measures (mainly the number of the wells of gas operation is taken into account.Pengaruh model problem based learning terhadap hasil belajar siswa pada materi statistika di kelas v sd negeri 3 peukan pidie
01 Apr 2022 - Pesona Dasar: Jurnal Pendidikan Dasar dan Humaniora
In this paper , the authors used quantitative approach and experiment by using pre-experimental designs (non-designs) and one shot case study to know the influence of Problem Based Learning Model toward the student achievement at statistical matery at grade V SD Negeri 3 Peukan Pidie.O enfoque transdisciplinar de Celso Furtado acerca do desenvolvimento econômico
01 Apr 2022 - Brazilian Journal of Political Economy
The authors argue that Furtado extrapolou, em sua formulação do processo de desenvolvimento, os limites da ciência econômica, divergindo, desse modo, dos modelos de crescimento económico convencionais.Increasing the Efficiency of The Romanian Tourism Sector by Improving the Service Management and using Mathematical Modeling
01 Apr 2022 - Valahian Journal of Economic Studies
In this paper , the authors present a survey on the development of the southeastern region of Romania through some important features in the increasingly challenging era of the prohibitions imposed by COVID 19, some knowledge which tries to answer the increasing complexity of economic and social realities, interactive and innovative approaches, analysis and promotion of the natural and anthropic potential of this tourist area and tourism enterprises, activities accomplished by them and attracting foreign investors, practices made public by managers in the tourism sector.Quantification de l’appréciation de l’humour par la simple observation visuelle
01 Apr 2022 - Revue Neurologique
In this article , Ehrlé et al. evaluated the applicabilité of applying visuelle analysis to quantifier l’appréciation de l'humour in patients cérébrolésés.Bilateral Female Inguinal Hernia Repair in Margaret Marquart Catholic Hospital and Review of Literature
01 Apr 2022 - Journal of the West African College of Surgeons
Emergency bilateral inguinal hernia repairs were three times associated with surgical site infection compared to elective repairs, and complications were the predominant complications and occurred more common after emergency repairs.Ophthalmic Photographers' Society Exhibit, July 2021.
01 Apr 2022 - Journal of Cataract and Refractive Surgery
In this paper , the authors proposed a new method for cataract and refractive surgery, which is called Cataract & Refractive Surgery (CRS), which can be found in the journal JCCR.Modern mini-invasive technologies in diagnostics and treatment of diseases of the hepatopancreatoduodenal zone
01 Apr 2022 - International Journal of Surgery
Amino acids are crucial building blocks of living organisms and together with their derivatives, they participate in many intracellular processes to act as hormones, neuromodulators, and neurotransmitters as discussed by the authors .Virtual special issue “microplastics 2022”
01 Apr 2022 - Journal of Hazardous Materials
In this paper , the rational designed Ag2S/SnS2 heterostructures were synthesized via a facile in-situ cation-exchange method, which enabled intimate atomic-level contact and strong electron coupling between SnS2 and Ag 2S, which efficiently assisted interfacial charge redistribution and transport as confirmed theoretically and experimentally.RIFM fragrance ingredient safety assessment, 3,5-dimethylcyclohexene-1-methanol, CAS Registry Number 67634-16-6.
A.M. Api, Donald V. Belsito, Danielle Botelho, Magnus Bruze, G. Allen Burton, M. A. Cancellieri, Hung-Che Chon, M.L. Dagli, M. Date, Wolfgang Dekant, C. Deodhar, Allison D. Fryer, L. Jones, K. Joshi, M. Kumar, A. Lapczynski, M. Lavelle, I-Pang Lee, Daniel C. Liebler, H. Moustakas, M. Na, B. Penning, G. Ritacco, J. Romine, N. Sadekar, Terry W Schultz, D. Selechnik, F. Siddiqi, I. Glenn Sipes, Gerry Sullivan, Y. Thakkar, Yoshinori Tokura
01 Apr 2022 - Food and Chemical Toxicology
• 3,5-dimethylcyclohexene-1-methanol; a safety assessment based on RIFM's criteria as mentioned in this paper , based on 7 human health endpoints plus environmental.Trending questions
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